MCCQE VALID EXAM VOUCHER | 100% FREE INTERACTIVE MCCQE PART 1 EXAM QUESTIONS

MCCQE Valid Exam Voucher | 100% Free Interactive MCCQE Part 1 Exam Questions

MCCQE Valid Exam Voucher | 100% Free Interactive MCCQE Part 1 Exam Questions

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Medical Council of Canada MCCQE Part 1 Exam Sample Questions (Q138-Q143):

NEW QUESTION # 138
An 18-year-old woman presents to the Emergency Department with a 3-day history of vomiting and right upper quadrant pain. She is alert but appears unwell and jaundiced. She was previously healthy and has not travelled recently. She has no risk factors for blood-borne pathogens. She denies hematemesis or hematochezia. On further history, she reports that she took a full bottle of pills that she found in her parents' medicine cabinet several hours before she started vomiting. Without intervention, which one of the following is the most likely outcome?

  • A. Ventricular fibrillation
  • B. Fulminant hepatic failure
  • C. Rapid-onset cerebral edema
  • D. Acute renal failure
  • E. Status epilepticus

Answer: B

Explanation:
This is a classic presentation of acute acetaminophen (paracetamol) overdose. The most serious consequence, especially with delayed treatment, is fulminant hepatic failure.
Toronto Notes 2023 - Toxicology, Acetaminophen Toxicity:
"Acetaminophen overdose is the most common cause of acute liver failure. Delayed presentation leads to jaundice, coagulopathy, encephalopathy, and possible death." MCCQE1 Objectives - Internal Medicine > Toxicology:
"Candidates must identify acetaminophen overdose by clinical history and recognize fulminant hepatic failure as a primary complication." Cerebral edema (C) may occur secondarily, but fulminant hepatic failure is the most direct and expected outcome. Renal failure (B), arrhythmias (E), and seizures (A) are not typical with acetaminophen.


NEW QUESTION # 139
A 63-year-old woman presents to your office with a history of progressive abdominal discomfort over the past five months. She reports bloating and difficult digestion with constipation. She has no urinary symptoms and denies vaginal or rectal bleeding. An abdominal ultrasound shows a large complex pelvic mass with internal multiloculation and moderate ascites. The cancer antigen 125 (CA 125) is elevated at 1023 U/mL (< 35 U
/mL). Which one of the following is the most likely diagnosis?

  • A. Rectosigmoid adenocarcinoma
  • B. Ovarian hyperstimulation syndrome
  • C. Metastatic uterine adenocarcinoma
  • D. Serous carcinoma of the ovary
  • E. Chronic hematosalpinx

Answer: D

Explanation:
Comprehensive and Detailed Explanation:
Postmenopausal women with abdominal distension, bloating, a complex pelvic mass, and elevated CA-125 are highly suggestive of epithelial ovarian cancer, especially serous cystadenocarcinoma-the most common type.
Toronto Notes 2023 - Gynecology / Oncology:
"Serous epithelial ovarian carcinoma presents with vague abdominal symptoms, ascites, complex pelvic mass, and elevated CA-125." MCCQE1 Objectives (Gynecology > 82-5: Ovarian Masses):
"Candidates must recognize signs and investigations of ovarian cancer, including elevated tumor markers and imaging findings." Ovarian hyperstimulation (A) occurs in fertility treatments. Colorectal cancer (C) may mimic these symptoms but typically causes rectal bleeding and has lower CA-125 levels. Uterine adenocarcinoma (D) usually causes bleeding. Hematosalpinx (E) presents with pelvic pain, not ascites.


NEW QUESTION # 140
A 34-year-old woman, gravida 3, para 2, aborta 0, presents at 38 weeks' gestation. She is in early labor with ruptured membranes. Her previous pregnancy was complicated by fever during labor. Which one of the following would increase the risk of fever recurrence?

  • A. Precipitous labor
  • B. Multiparity
  • C. Epidural analgesia
  • D. Advanced maternal age

Answer: C

Explanation:
Comprehensive and Detailed Explanation:
Epidural analgesia is associated with increased maternal intrapartum fever due to non-infectious(neurogenic) thermoregulation impairment. This is a well-known phenomenon in laboring women.
Toronto Notes 2023 - Obstetrics / Anesthesia:
"Epidural analgesia increases risk of intrapartum fever by up to 20% via non-infectious mechanisms." MCCQE1 Objectives (Obstetrics > 80-5: Intrapartum Care):
"Candidates must recognize risk factors for intrapartum complications, including effects of epidural use." Multiparity (A), precipitous labor (B), and maternal age (C) are not established risk factors for intrapartum fever.


NEW QUESTION # 141
The parents of a 12-year-old boy present to your clinic to discuss their son's submersion injury. The patient was seen in hospital for 6 months after being pulled unresponsive from a lake at his friend's house; he had been submerged for an estimated 20 minutes. After extended resuscitation and a 2-month stay in the intensive care unit, he remains in a persistent vegetative state but needs no respiratory or cardiac support. When evaluating the discharge from hospital, which one of the following is most appropriate?

  • A. Plan for a progressive return to school with a home caregiver
  • B. Organize scheduled readmissions to hospital to provide the family with respite care
  • C. Advocate for home care support so that the parents can care for their son safely at home
  • D. Recommend placement in a palliative care facility
  • E. Continue intensive rehabilitation in the acute care hospital for the best chance of recovery

Answer: C

Explanation:
Comprehensive and Detailed Explanation:
The patient is in a persistent vegetative state and medically stable, meaning he does not need continued hospitalization. The goal is to provide appropriate long-term care in the least restrictive setting, typically at home with robust home care support services. This approach aligns with ethical care, family-centered goals, and medical appropriateness.
Toronto Notes 2023 - Pediatrics / Neurodevelopment & Chronic Care:
"Home care with appropriate medical and caregiver support is often the best setting for children with severe neurological impairments who are medically stable." MCCQE1 Objectives (Pediatrics > 77-5: Chronic Neurological Disorders):
"Candidates must assess discharge planning and coordinate home care support for children with long-term care needs." Palliative facility (B) is not appropriate unless end-of-life is imminent. School (C) is not feasible in this state.
Hospital readmission for respite (D) is not standard. Rehabilitation (E) has little utility in persistent vegetative state.
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NEW QUESTION # 142
A patient's mother comes to you with a prospective cohort study linking autism to the measles, mumps and rubella vaccine. After reviewing the study carefully, you question the results because of problems with the study design and execution. Which one of the following sources of error would be most important in the study design or execution?

  • A. Not accounting for all potential confounders during recruitment
  • B. Recruitment of study families at an autism seminar
  • C. Reporting standard error with point estimates of difference
  • D. Parental recall of vaccine administration
  • E. Vaccine company sponsorship of study

Answer: B

Explanation:
Recruiting participants from an autism seminar introduces selection bias. This non-random selection increases the likelihood of overestimating associations due to pre-existing beliefs or exposures in that subgroup.
Toronto Notes 2023 - Epidemiology:
"Selection bias occurs when participants are not representative of the general population, as in recruitment from disease-specific support groups." MCCQE1 Objectives (Population Health > 65-2: Study Design and Appraisal):
"Candidates must recognize sources of bias in epidemiologic studies, including selection bias due to non- representative recruitment." Recall bias (D) is more of a concern in retrospective studies. Sponsorship (B) may create perception bias but is not a flaw in methodology itself. Standard error reporting (A) is normal. Not accounting for confounders (E) matters but recruitment source is more directly biasing.


NEW QUESTION # 143
......

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